Predictive modeling of biological responses in the rat liver using in vitro Tox21 bioactivity: Benefits from high-throughput toxicokinetics

Author:

Ring Caroline,Sipes Nisha S.,Hsieh Jui-Hua,Carberry Celeste,Koval Lauren E.,Klaren William D.,Harris Mark A.,Auerbach Scott S.,Rager Julia E.

Funder

National Institute of Environmental Health Sciences

Publisher

Elsevier BV

Subject

Health, Toxicology and Mutagenesis,Computer Science Applications,Toxicology

Reference66 articles.

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3. NAS. Toxicity Testing in the 21st Century: A Vision and A Strategy. Washington, DC: Committee on Toxicity Testing and Assessment of Environmental Agents, National Research Council, 2007 ISBN 978-0-309-10992-5.

4. NAS. Using 21st Century Science to Improve Risk-Related Evaluations. Washington, DC: Committee on Incorporating 21st Century Science into Risk-Based Evaluations; Board on Environmental Studies and Toxicology; Division on Earth and Life Studies; National Academies of Sciences, Engineering, and Medicine, 2017 ISBN 978-0-309-45348-6.

5. EPA US. Efforts to Reduce Animal Testing at EPA 2019 [cited 2020 Jan 3]. Available from: https://www.epa.gov/research/efforts-reduce-animal-testing-epa.

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