Metabolites downstream of predicted loss-of-function variants inform relationship to disease-Reference-Cited by-同舟云学术

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Metabolites downstream of predicted loss-of-function variants inform relationship to disease

Published:2019-12 Issue:4 Volume:128 Page:476-482
ISSN:1096-7192
Container-title:Molecular Genetics and Metabolism
language:en
Short-container-title:Molecular Genetics and Metabolism

Author:

Li Mengbo,Wang Andy,Quek Lake-Ee,Vernon Stephen,Figtree Gemma A.,Yang Jean,O'Sullivan John F.

Funder

Heart Research Institute

Sydney Medical School Foundation

NSW Health

National Heart, Lung, and Blood Institute

Boston University

Massachusetts General Hospital

Publisher

Elsevier BV

Subject

Endocrinology,Genetics,Molecular Biology,Biochemistry,Endocrinology, Diabetes and Metabolism

Reference64 articles.

1. Analysis of predicted loss-of-function variants in UK Biobank identifies variants protective for disease;Emdin;Nat. Commun.,2018

2. A genome-wide association study of the human metabolome in a community-based cohort;Rhee;Cell Metab.,2013

3. A genome-wide association study of metabolic traits in human urine;Suhre;Nat. Genet.,2011

4. Indole and indoxyl sulfate, gut bacteria metabolites of tryptophan, change arterial blood pressure via peripheral and central mechanisms in rats;Huc;Pharmacol. Res.,2018

5. Indoxyl sulfate-induced activation of (pro)renin receptor is involved in expression of TGF-beta1 and alpha-smooth muscle actin in proximal tubular cells;Saito;Endocrinology,2014

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