Negative correlation between organ heteroplasmy, particularly hepatic heteroplasmy, and age at death revealed by post-mortem studies of m.3243A

Negative correlation between organ heteroplasmy, particularly hepatic heteroplasmy, and age at death revealed by post-mortem studies of m.3243A > G cases

Published:2023-11 Issue:3 Volume:140 Page:107691
ISSN:1096-7192
Container-title:Molecular Genetics and Metabolism
language:en
Short-container-title:Molecular Genetics and Metabolism

Author:

Yagi Kunimasa,Okazaki Satoko,Ohbatake Azusa,Nakaya Masako,Liu Jianhui,Arite Eiko,Miyamoto Yukiko,Ito Naoko,Nakano Kaoru,Yamaaki Naoto,Honoki Hisae,Fujisaka Shiho,Chujo Daisuke,Tsunoda Shin-ichiro,Yanagimoto Kunio,Nozue Tsuyoshi,Yamada Masayo,Ooe Kotaro,Araki Tsutomu,Nakashima Akikatsu,Azami Yasushi,Sodemoto Yukio,Tadokoro Kenichi,Nagano Makoto,Noguchi Tohru,Nohara Atushi,Origasa Hideki,Niida Yo,Tada Hayato

Funder

Japan Society for the Promotion of Science

Kanazawa University

Publisher

Elsevier BV

Subject

Endocrinology,Genetics,Molecular Biology,Biochemistry,Endocrinology, Diabetes and Metabolism

Reference58 articles.

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3. Maternally inherited diabetes and deafness is a distinct subtype of diabetes and associates with a single point mutation in the mitochondrial tRNA(Leu(UUR)) gene;van den Ouweland;Diabetes.,1994

4. Causes of death in pedigrees with the 3243A>G mutation in mitochondrial DNA;Majamaa-Voltti;J. Neurol. Neurosurg. Psychiatry,2008

5. Epidemiology of A3243G, the mutation for mitochondrial encephalomyopathy, lactic acidosis, and strokelike episodes: prevalence of the mutation in an adult population;Majamaa;Am. J. Hum. Genet.,1998

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