A phase 3, multicenter, open-label, randomized study of abarelix versus leuprolide acetate in men with prostate cancer

Author:

McLeod David,Zinner Norman,Tomera Kevin,Gleason Donald,Fotheringham Nick,Campion Marilyn,Garnick Marc B

Publisher

Elsevier BV

Subject

Urology

Reference5 articles.

1. Abarelix depot, a GnRH antagonist, vs leuprolide or goserelin, LHRH agonists;Tomera;J Urol,2001

2. Garnick MB, Tomera K, Campion M, et al: Abarelix-depot (A-D), a sustained release (SR) formulation of a potent GnRH pure antagonists in patients (pts) with prostate cancer (PrCA): phase II clinical results and endocrine comparison with agonists Lupron (L) and Zoladex (Z) (abstract). J Urol 161(4 suppl): 340, 1999.

3. Abarelix depot-M, a GnRH superagonist, versus LHRH superagonists in prostate cancer;Garnick;Mol Urol,2000

4. Garnick MB, Gittleman M, Steidle C, et al: Abarelix (PPI-149), a novel and potent GnRH antagonist, induces a rapid and profound prostate gland volume reduction (PGVR) and androgen suppression before brachytherapy (BT) or radiation therapy (XPT) (abstract). J Urol 159(5 suppl): 220, 1998.

5. Hormone-refractory prostate cancer cells express functional follicle-stimulating hormone receptor (FSHR);Ben-Josef;J Urol,1999

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