Dose-dependent hypolipidemic effect of an inhibitor of HMG-CoA reductase, pravastatin (CS-514), in hypercholesterolemic subjects A double blind test

Author:

Saito Yasushi,Goto Yuichiro,Nakaya Noriaki,Hata Yoshiya,Homma Yasuhiko,Naito Chikayuki,Hayashi Hiroshi,Ito Hiroo,Yamamoto Minoru,Takeuchi Ichiro,Mori Kohsuke,Hara Tsutomu,Yoshiya Sho,Shirai Kohji,Sasaki Norihiro,Shinomiya Masaki,Murano Shunichi,Morisaki Nobuhiro,Nishiide Toshio,Kanzaki Tetsuto,Watanabe Naoko,Ishikawa Toshitsugu

Publisher

Elsevier BV

Subject

Cardiology and Cardiovascular Medicine

Reference23 articles.

1. Predisposition to atherosclerosis in the head, heart and legs - The Framingham study;Gordon;J. Amer. Med. Assoc.,1972

2. Treatment of hypercholesterolemia;Grundy;Amer. J. Clin. Nutr.,1977

3. Competitive inhibition of 3-hydroxy-3-methylglutaryl coenzyme A reductase by ML-236A and ML-23613, fungal metabolites having hypocholesterolemic activity;Endo;FEBS Lett.,1976

4. Therapeutic effects of ML236B in primary hypercholesterolemia;Yamamoto;Atherosclerosis,1980

5. Mevinolin: a highly potent competitive inhibitor of 3-hydroxy 3-methylglutaryl coenzyme A reductase and a cholesterol-lowering agent;Alberts,1980

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