Rapid and substantial lowering of human serum cholesterol by mevinolin (MK-803), an inhibitor of hydroxymethylglutaryl-coenzyme a reductase

Author:

Tobert J.A.,Hitzenberger G.,Kukovetz W.R.,Holmes I.B.,Jones K.H.

Publisher

Elsevier BV

Subject

Cardiology and Cardiovascular Medicine

Reference12 articles.

1. Predisposition to atherosclerosis in the head, heart, and legs — The Framingham study;Gordon;J. Amer. Med. Ass.,1972

2. Treatment of hypercholesterolemia;Grundy;Amer. J. Clin. Nutr.,1977

3. Mevinolin—A highly potent competitive inhibitor of hydroxymethylglutaryl -coenzyme A reductase and a cholesterol-lowering agent;Alberts,1980

4. Regulation of HMG-CoA reductase;Rodwell;Adv. Lipid Res.,1976

5. Comparison of two new developed enzymatic cholesterol-colortests on autoanalyzer-systems with other cholesterol tests;Klose;Clin. Chem.,1975

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