A single amino acid substitution in MSH5 results in DNA alkylation tolerance

Author:

Bawa Sonya,Xiao Wei

Publisher

Elsevier BV

Subject

Genetics,General Medicine

Reference27 articles.

1. Genetic and biochemical analysis of Msh2p–Msh6p: role of ATP hydrolysis and Msh2p–Msh6p subunit interactions in mismatch base pair recognition;Alani;Mol. Cell. Biol.,1997

2. N-(2-Chloroethyl)-N′-cyclohexyl-N-nitrosourea sensitivity in mismatch repair-defective human cells;Aquilina;Cancer Res.,1998

3. A mutation in the MSH5 gene results in alkylation tolerance;Bawa;Cancer Res.,1997

4. Disruption of the helix-u-turn-helix motif of MutS protein: loss of subunit dimerization, mismatch binding and ATP hydrolysis;Biswas;J. Mol. Biol.,2001

5. Defective mismatch binding and a mutator phenotype in cells tolerant to DNA damage;Branch;Nature,1993

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