The effect of vesnarinone on TNFα production in human peripheral blood mononuclear cells and microglia: a preclinical study for the treatment of multiple sclerosis

Author:

Jiang H,Bielekova B,Okazaki H,Clarence-Smith K,Johnson K.P,Bergey G,Martin R,Dhib-Jalbut S

Publisher

Elsevier BV

Subject

Neurology (clinical),Neurology,Immunology,Immunology and Allergy

Reference26 articles.

1. T-cell tumor necrosis factor-alpha receptor binding in patients with multiple sclerosis;Bongioanni;Neurology,1997

2. Hypothesis: a role for tumor necrosis factor in immune-mediated demyelination and its relevance to multiple sclerosis;Brosnan;J. Neuroimmunol.,1988

3. Interferon-gamma modulates the lipopolysaccharide-induced expression of AP-1 and NF-kappa B at the mRNA and protein level in human monocytes;de Wit;Exp. Hematol.,1996

4. Effects of Vesnarinone on morbidity and mortality in patients with heart failure;Feldman;N. Engl. J. Med.,1993

5. Prevention of autoimmune demyelination in non-human primates by a cAMP-specific phosphodiesterase inhibitor;Genain;Proc. Natl. Acad. Sci. USA,1995

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