The pharmacokinetic study on the mechanism of toxicity attenuation of rhubarb total free anthraquinone oral colon-specific drug delivery system

Author:

Zhang Lin,Chang Jin-hua,Zhang Bao-qi,Liu Xi-gang,Liu Pei,Xue He-fei,Liu Li-yan,Fu Qiang,Zhu Meng,Liu Cui-zhe

Funder

National Natural Science Foundation of China

Key Discipline Construction Projects of Higher School

Hebei Province Natural Science Foundation of China

Science and Technology Research Key Project of Higher School in Hebei Province

Science and Technology Research Youth Fund Project of Higher School in Hebei Province

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology,General Medicine

Reference13 articles.

1. The Pharmacopoeia Commission of People's Republic of China, Pharmacopoeia of the People's Republic of China,2010

2. Chemical Composition and Pharmacological Effects of Traditional Chinese Medicine;People's Health Press,1996

3. The diarrhoeogenic and antidiarrhoeal bidirectional effects of rhubarb and its potential mechanism[J];Qin;J. Ethnopharmacol.,2011

4. Design and evaluation of San-huang dispersible tablet—an efficient delivery system for traditional Chinese medicine[J];Liu;Pharm. Dev. Technol.,2009

5. Study on the Cathartic Effect of Anthraquinones by Colon-Targeted Drug Delivery and Pharmacokinetics of Anthraquinone Extractions of Rhubarb[D];Zhang,2010

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