Microbial transformation of osthole by human intestinal fungi and anti-osteoporosis activities of its metabolites

Author:

He Xin,Nie Min,Wang Mengyuan,Wu Shifei,Wei Xuemei,Li Jiayuan,Yao Changliang,Wang Chao,Ma Xiaochi,Guo De-an

Funder

National Natural Science Foundation of China

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology,General Medicine

Reference20 articles.

1. Osthole: a multifunctional natural compound with potential anticancer, antioxidant and anti-inflammatory activities;Zafar;Mini-Rev. Med. Chem.,2021

2. Osthole promotes neuronal differentiation and inhibits apoptosis via Wnt/β-catenin signaling in an Alzheimer's disease model;Yao;Toxicol. Appl. Pharmacol.,2015

3. Osthole attenuates hepatic injury in a rodent model of trauma-hemorrhage;Yu;PLoS One,2018

4. Antiproliferative effect of isopentenylated coumarins on several cancer cell lines;Kawaii;Anticancer Res.,2001

5. Osthol, a coumarin isolated from common cnidium fruit, enhances the differentiation and maturation of osteoblasts in vitro;Ming;Pharmacology.,2011

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