Lipid peroxidation and cell viability in isolated hepatocytes in a redesigned oxystat system: Evaluation of the hypothesis that lipid peroxidation, preferentially induced at low oxygen partial pressures, is decisive for CCl4 liver cell injury-Reference-Cited by-同舟云学术

Lipid peroxidation and cell viability in isolated hepatocytes in a redesigned oxystat system: Evaluation of the hypothesis that lipid peroxidation, preferentially induced at low oxygen partial pressures, is decisive for CCl4 liver cell injury

Published:1988-08 Issue:2 Volume:264 Page:591-599
ISSN:0003-9861
Container-title:Archives of Biochemistry and Biophysics
language:en
Short-container-title:Archives of Biochemistry and Biophysics

Author:

De Groot Herbert,Littauer Andrea,Hugo-Wissemann Doris,Wissemann Peter,Noll Thomas

Publisher

Elsevier BV

Subject

Molecular Biology,Biochemistry,Biophysics

Reference37 articles.

1. Oxygen- and carbon-centered free radical formation during carbon tetrachloride metabolism. Observation of lipid radicals in vivo and in vitro.

2. Pathological mechanisms in carbon tetrachloride hepatotoxicity

3. Biochemical studies on the metabolic activation of halogenated alkanes.

4. The formation of a novel free radical metabolite from CCl4 in the perfused rat liver and in vivo.

5. The mechanism of chloroform and carbon monoxide formation from carbon tetrachloride by microsomal cytochrome P-450

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