HMG-CoA reductase activity in human liver microsomes: comparative inhibition by statins

Author:

Dansette P.M.,Jaoen M.,Pons C.

Publisher

Elsevier BV

Subject

Cell Biology,Toxicology,General Medicine,Pathology and Forensic Medicine

Reference23 articles.

1. A highly potent competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase and a cholesterol-lowering agent;Alberts;Proc.Natl Acad Sci USA,1980

2. High enzyme affinity and active metabolites contribute to its high pharmacological activity;Bischoff;Atherosclerosis,1997

3. Metabolism of cerivastatin by human liver microsomes in vitro.Characterization of primary metabolic pathways and of cytochrome P450 isozymes involved;Boberg;Drug Metab Dispo,1997

4. HMGCoA reductase and cholesterol 7α-hydroxylase in human liver;Bosisio;Life Sci,1984

5. Active and inactive forms of 3-hydroxy-3-methylglutaryl coenzyme A reductase in the liver of the rat;Brown;J Biol Chem,1979

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