A homogeneous time-resolved fluorescence-based high-throughput screening system for discovery of inhibitors of IKKβ–NEMO interaction
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry,Biophysics
Reference28 articles.
1. A cytokine-responsive IκB kinase that activates the transcription factor NF-κB;DiDonato;Nature,1997
2. Direct phosphorylation of IκB by IKKα and IKKβ: discrimination between free and NF-κB-bound substrate;Zandi;Science,1998
3. The IκB kinase complex (IKK) contains two kinase subunits, IKKα and IKKβ, necessary for IκB phosphorylation and NF-κB activation;Zandi;Cell,1997
4. IKK-1 and IKK-2: cytokine-activated IκB kinases essential for NF-κB activation;Mercurio;Science,1997
5. IKK-γ is an essential regulatory subunit of the IκB kinase complex;Rothwarf;Nature,1998
Cited by 15 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Development of a Decafluorobiphenyl Cyclized Peptide Targeting the NEMO–IKKα/β Interaction that Enhances Cell Penetration and Attenuates Lipopolysaccharide-Induced Acute Lung Injury;Bioconjugate Chemistry;2024-04-26
2. Identification of first active compounds in drug discovery. how to proceed?;Frontiers in Drug Discovery;2024-01-25
3. The IKK-binding domain of NEMO is an irregular coiled coil with a dynamic binding interface;Scientific Reports;2019-02-27
4. Cell-Permeable Bicyclic Peptidyl Inhibitors against NEMO-IκB Kinase Interaction Directly from a Combinatorial Library;Journal of the American Chemical Society;2018-09-03
5. Rapid LC-MS Based High-Throughput Screening Method, Affording No False Positives or False Negatives, Identifies a New Inhibitor for Carbonic Anhydrase;Scientific Reports;2017-09-04
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3