Sterol-regulated ubiquitination and degradation of Insig-1 creates a convergent mechanism for feedback control of cholesterol synthesis and uptake
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Physiology
Reference32 articles.
1. Cholesterol and 25-hydroxycholesterol inhibit activation of SREBPs by different mechanisms, both involving SCAP and insigs;Adams;J. Biol. Chem.,2004
2. Niemann-Pick C1 like 1 protein is critical for intestinal cholesterol absorption;Altmann;Science,2004
3. Cholesterol addition to ER membranes alters conformation of SCAP, the SREBP escort protein that regulates cholesterol metabolism;Brown;Mol. Cell,2002
4. A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood;Brown;Proc. Natl. Acad. Sci. USA,1999
5. Ubiquitin signalling in the NF-κB pathway;Chen;Nat. Cell Biol.,2005
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