Exome Sequencing Identifies Genes and Gene Sets Contributing to Severe Childhood Obesity, Linking PHIP Variants to Repressed POMC Transcription

Author:

Marenne Gaëlle,Hendricks Audrey E.,Perdikari Aliki,Bounds Rebecca,Payne Felicity,Keogh Julia M.,Lelliott Christopher J.,Henning Elana,Pathan Saad,Ashford Sofie,Bochukova Elena G.,Mistry Vanisha,Daly Allan,Hayward Caroline,Wareham Nicholas J.,O’Rahilly Stephen,Langenberg Claudia,Wheeler Eleanor,Zeggini Eleftheria,Farooqi I. Sadaf,Barroso Inês

Funder

National Institute for Health Research

Cambridge University Hospitals NHS Foundation Trust

Wellcome Trust

Medical Research Council

British Heart Foundation

Engineering and Physical Sciences Research Council

Economic and Social Research Council

Department of Health and Social Care

Chief Scientist Office

Health and Social Care Research and Development Division

Public Health Agency

National Institutes of Health

NCI

NHGRI

NHLBI

NIDA

NIMH

NINDS

Swiss National Science Foundation

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Physiology

Reference68 articles.

1. A map of human genome variation from population-scale sequencing;Abecasis;Nature,2010

2. Genome-wide association study identifies 112 new loci for body mass index in the Japanese population;Akiyama;Nat. Genet.,2017

3. The heritability of body mass index among an international sample of monozygotic twins reared apart;Allison;Int. J. Obes. Relat. Metab. Disord.,1996

4. How to perform a meta-analysis with R: a practical tutorial;Balduzzi;Evid. Based Ment. Health,2019

5. The genetic basis of metabolic disease;Barroso;Cell,2019

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