A Gut Feeling for Metformin

Author:

Cherney David Z.I.,Lam Tony K.T.

Funder

Canadian Institutes of Health Research

Diabetes Canada

Juvenile Diabetes Research Foundation

Canadian Diabetes Association

Banting and Best Diabetes Centre

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Physiology

Reference12 articles.

1. Metformin alters upper small intestinal microbiota that impact a glucose-SGLT1-sensing glucoregulatory pathway;Bauer;Cell Metab.,2018

2. Lactobacillus gasseri in the upper small intestine impacts an ACSL3-dependent fatty acid-sensing pathway regulating whole-body glucose homeostasis;Bauer;Cell Metab.,2018

3. Comparative effects of proximal and distal small intestinal administration of metformin on plasma glucose and glucagon-like peptide-1, and gastric emptying after oral glucose, in type 2 diabetes;Borg;Diabetes Obes. Metab.,2018

4. The primary glucose-lowering effect of metformin resides in the gut, not the circulation: results from short-term phar- macokinetic and 12-week dose-ranging studies;Buse;Diabetes Care,2016

5. Mechanisms of action and therapeutic application of glucagon-like peptide-1;Drucker;Cell Metab.,2018

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