The Immunomodulatory Metabolite Itaconate Modifies NLRP3 and Inhibits Inflammasome Activation-Reference-Cited by-同舟云学术

The Immunomodulatory Metabolite Itaconate Modifies NLRP3 and Inhibits Inflammasome Activation

Published:2020-09 Issue:3 Volume:32 Page:468-478.e7
ISSN:1550-4131
Container-title:Cell Metabolism
language:en
Short-container-title:Cell Metabolism

Author:

Hooftman Alexander,Angiari Stefano,Hester Svenja,Corcoran Sarah E.,Runtsch Marah C.,Ling Chris,Ruzek Melanie C.,Slivka Peter F.,McGettrick Anne F.,Banahan Kathy,Hughes Mark M.,Irvine Alan D.,Fischer Roman,O’Neill Luke A.J.

Funder

Science Foundation Ireland

Wellcome Trust

European Research Council

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Physiology

Reference57 articles.

1. PtdIns4P on dispersed trans-Golgi network mediates NLRP3 inflammasome activation;Chen;Nature,2018

2. A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases;Coll;Nat. Med.,2015

3. Immunoresponsive gene 1 and itaconate inhibit succinate dehydrogenase to modulate intracellular succinate levels;Cordes;J. Biol. Chem.,2016

4. Changes in plasma itaconate elevation in early rheumatoid arthritis patients elucidates disease activity associated macrophage activation;Daly;Metabolites,2020

5. The intracellular chloride channel proteins CLIC1 and CLIC4 induce IL-1β transcription and activate the NLRP3 inflammasome;Domingo-Fernández;J. Biol. Chem.,2017

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