Ribonucleotide reductase M2 subunit silencing suppresses tumorigenesis in pancreatic cancer via inactivation of PI3K/AKT/mTOR pathway-Reference-Cited by-同舟云学术

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Ribonucleotide reductase M2 subunit silencing suppresses tumorigenesis in pancreatic cancer via inactivation of PI3K/AKT/mTOR pathway

Published:2022-04 Issue:3 Volume:22 Page:401-413
ISSN:1424-3903
Container-title:Pancreatology
language:en
Short-container-title:Pancreatology

Author:

Shan Jinlan,Wang Zhen,Mo Qiuping,Long Jingpei,Fan Yangfan,Cheng Lu,Zhang Tao,Liu Xiyong,Wang Xiaochen

Funder

Natural Science Foundation of Zhejiang Province

Publisher

Elsevier BV

Subject

Gastroenterology,Hepatology,Endocrinology, Diabetes and Metabolism

Reference51 articles.

1. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries;Sung;CA A Cancer J Clin,2021

2. St. Gallen EORTC Gastrointestinal Cancer Conference: consensus recommendations on controversial issues in the primary treatment of pancreatic cancer;Lutz;Eur J Cancer,2017

3. Nucleoside analogue triphosphates allosterically regulate human ribonucleotide reductase and identify chemical determinants that drive substrate specificity;Knappenberger;Biochemistry,2016

4. siRNA knockdown of RRM2 effectively suppressed pancreatic tumor growth alone or synergistically with doxorubicin;Zheng;Mol Ther Nucleic Acids,2018

5. ATR-CHK1-E2F3 signaling transactivates human ribonucleotide reductase small subunit M2 for DNA repair induced by the chemical carcinogen MNNG;Gong;Biochim Biophys Acta,2016

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