Quercetin protects against intestinal barrier disruption and inflammation in acute necrotizing pancreatitis through TLR4/MyD88/p38 MAPK and ERS inhibition

Author:

Junyuan Zheng,Hui Xu,Chunlan Huang,Junjie Fan,Qixiang Mei,Yingying Lu,Lihong Lou,Xingpeng Wang,Yue Zeng

Funder

Shanghai Jiao Tong University

Natural ScienceFoundation for Young Scholars of China

Publisher

Elsevier BV

Subject

Gastroenterology,Hepatology,Endocrinology, Diabetes and Metabolism

Reference43 articles.

1. Dysbiosis of intestinal microbiota and decrease in paneth cell antimicrobial peptide level during acute necrotizing pancreatitis in rats;Chen;PLoS One,2017

2. Role of the gut barrier in acute pancreatitis;Capurso;J Clin Gastroenterol,2012

3. TLR4 at the crossroads of nutrients, gut microbiota, and metabolic inflammation;Velloso;Endocr Rev,2015

4. Toll-like receptors in pathophysiology of liver disease;Kiziltas;World J Hepatol,2016

5. They must hold tight: junction proteins, microbiota and immunity in intestinal mucosa;Castoldi;Curr Protein Pept Sci,2015

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