Shikonin-mediated PD-L1 degradation suppresses immune evasion in pancreatic cancer by inhibiting NF-κB/STAT3 and NF-κB/CSN5 signaling pathways

Author:

Ruan Zhiyan,Liang Minhua,Shang Ling,Lai Manxiang,Deng Xiangliang,Su Xinguo

Publisher

Elsevier BV

Subject

Gastroenterology,Hepatology,Endocrinology, Diabetes and Metabolism

Reference56 articles.

1. MicroRNA-221 induces autophagy through suppressing HDAC6 expression and promoting apoptosis in pancreatic cancer;Yang;Oncol Lett,2018

2. Hypoxia potentiates gemcitabine-induced stemness in pancreatic cancer cells through AKT/Notch1 signaling;Zhang;J Exp Clin Canc Res,2018

3. Overcoming immune evasion in pancreatic cancer: the combination matters;Michl;Gut,2018

4. Immune evasion in pancreatic cancer: from mechanisms to therapy;Martinez-Bosch;Cancers,2018

5. PD-1/PD-L1 and immunotherapy for pancreatic cancer;Feng;Canc Lett,2017

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