Coexpression of B7-1 and viral (“self”) transgenes in pancreatic β cells can break peripheral ignorance and lead to spontaneous autoimmune diabetes

Author:

von Herrath Matthias G.,Guerder Sylvia,Lewicki Hanna,Flavell Richard A.,Oldstone Michael B.A.

Publisher

Elsevier BV

Subject

Infectious Diseases,Immunology,Immunology and Allergy

Reference45 articles.

1. CD28-B7 interactions in T cell activation;Allison;Curr. Opin. Immunol.,1994

2. Human diabetes;Baekkeskov;Curr. Topics Microbiol. Immunol.,1990

3. Analysis of IL-2, IL-4, and IFNγ producing cells in situ during immune responses to protein antigens;Bogen;J. Immunol.,1993

4. Blockade of the CD28 costimulatory pathway: a means to induce tolerance;Boussiotis;Curr. Opin. Immunol.,1994

5. In vitro induction of T cell energy by blocking B7 and early T cell costimulatory molecule ETC-1/87-2;Chen;Immunity,1994

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