A genetically engineered single-chain FVTNF molecule possesses the anti-tumor immunoreactivity of FV as well as the cytotoxic activity of tumor necrosis factor

Author:

Yang Jungbao,Moyana Terence,Xiang Jim

Publisher

Elsevier BV

Subject

Molecular Biology,Immunology

Reference44 articles.

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2. Studies on the anti-tumor efficacy of systemically administered recombinant tumor necrosis factor against several murine tumors in vivo;Asher;J. Immunol.,1987

3. Intralesional application of recombinant human tumor necrosis factor alpha induces local tumor regression in patients with advanced malignancies;Bartsch;Eur. J. Cancer clin. Oncol.,1989

4. Tumor suppression after tumor cell-targeted tumor necrosis factor gene transfer;Blankenstein;J. exp. Med.,1991

5. Renaturation, purification and characterization of recombinant Fab fragment produced in Escherichia coli;Buchner;Bio/Tech.,1991

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