Are single-dose toxicology studies in animals adequate to support single doses of a new drug in humans?

Author:

Monro Alastair,Mehta Dilip

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology

Cited by 16 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Pathology Issues in the Design of Toxicology Studies;Haschek and Rousseaux's Handbook of Toxicologic Pathology;2013

2. Comparison of whole body and head out plethysmography using respiratory stimulant and depressant in conscious rats;Journal of Pharmacological and Toxicological Methods;2012-01

3. Predicting Human Adverse Drug Reactions from Nonclinical Safety Studies;Pharmaceutical Sciences Encyclopedia;2010-03-15

4. 1. The History of Microdose Clinical Trials;Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics;2009

5. Roles of Translational Research in Pharmaceutical Companies: Toward Improvement of Productivity in Pharmaceutical Research & Development through Paradigm Shift;Journal of the Mass Spectrometry Society of Japan;2009

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