Antipyrine as a probe for human oxidative drug metabolism: Identification of the cytochrome P450 enzymes catalyzing 4-hydroxyantipyrine, 3-hydroxymethylantipyrine, and norantipyrine formation*-Reference-Cited by-同舟云学术

Antipyrine as a probe for human oxidative drug metabolism: Identification of the cytochrome P450 enzymes catalyzing 4-hydroxyantipyrine, 3-hydroxymethylantipyrine, and norantipyrine formation*

Published:1996-06 Issue:6 Volume:59 Page:613-623
ISSN:0009-9236
Container-title:Clinical Pharmacology & Therapeutics
language:
Short-container-title:Clin Pharmacol Ther

Author:

Engel Georg,Hofmann Ute,Heidemann Hugo,Cosme Jose,Eichelbaum Michel

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology

Reference44 articles.

1. The role of individual human cytochrpmes P450 in drug metabolism and clinical response

2. Role of human hepatic cytochromes P450 in drug metabolism and toxicity

3. Assessment of the drug metabolism capacity of the liver.

4. The model drug approach in clinical pharmacology

5. The antipyrine test in clinical pharmacology: Conceptions and misconceptions

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