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EGCG and ECG induce apoptosis and decrease autophagy via the AMPK/mTOR and PI3K/AKT/mTOR pathway in human melanoma cells

  • Published:2022-04 Issue:4 Volume:20 Page:290-300
  • ISSN:1875-5364
  • Container-title:Chinese Journal of Natural Medicines
  • language:en
  • Short-container-title:Chinese Journal of Natural Medicines

Author:

DU Bing-Xin,LIN Pei,LIN Jun

Funder

National Natural Science Foundation of China

Fundamental Research Funds for the Central Universities

Publisher

Elsevier BV

Subject

Complementary and alternative medicine,Drug Discovery,General Medicine

Reference48 articles.

1. Panduratin A induces protective autophagy in melanomaviathe AMPK and mTOR pathway;Lai;Phytomedicine,2018

2. Capsaicin induces apoptosis and autophagy in human melanoma cells;Chu;Oncol Lett,2019

3. Resveratrol suppresses melanoma growth by promoting autophagy through inhibiting the PI3K/AKT/mTOR signaling pathway;Gong;Exp Ther Med,2020

4. Hibiscus sabdariffa leaf polyphenolic extract induces human melanoma cell death, apoptosis, and autophagy;Chiu;J Food Sci,2015

5. Sasanquasaponin III from Schima crenata Korth induces autophagy through Akt/mTOR/p70S6K pathway and promotes apoptosis in human melanoma A375 cells;Liang;Phytomedicine,2019

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