The discovery of orally available thrombin inhibitors: Optimisation of the P1 pharmacophore-Reference-Cited by-同舟云学术

The discovery of orally available thrombin inhibitors: Optimisation of the P1 pharmacophore

Published:1999-04 Issue:8 Volume:9 Page:1103-1108
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Ambler John,Bentley David,Brown Lyndon,Dunnet Karen,Farr Dave,Janus Diana,Grand Darren Le,Menear Keith,Mercer Mark,Talbot Mark,Tweed Morris,Wathey Bernard

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference8 articles.

1. Thrombin and factor Xa inhibitors;Kaiser;Drugs of the Future,1998

2. Heparins

3. Pharmacological profile of low molecular weight heparins: implications in prophylaxis and the treatment of thrombotic disorders;Fareed,1992

4. Small molecule direct thrombin inhibitors;Wiley;Expert Opin. Ther. Pat.,1997

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