Synthesis and structure-activity relationships of novel THF 1β-methylcarbapenems-Reference-Cited by-同舟云学术

Synthesis and structure-activity relationships of novel THF 1β-methylcarbapenems

Published:1997-07 Issue:13 Volume:7 Page:1671-1676
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Lin Yang-I,Bitha Panayota,Sakya Subas M.,Strohmeyer Timothy W.,Li Zhong,Lee Ving J.,Lang Stanley A.,Yang Youjun,Bhachech Niraja,Weiss William J.,Petersen Peter J.,Jacobus Nilda V.,Bush Karen,Testa Raymond T.,Tally Francis P.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference24 articles.

1. The carbapenems: new broad spectrum -lactam antibiotics

2. In-vitro activity of new carbapenem antibiotics: comparative studies with meropenem, L-627 and imipenem against pathogenic Nocardia spp.

3. Structure-activity Relationships for Interactions between Carbapenems and .BETA.-Lactamases.

4. Biochemical comparison of imipenem, meropenem and biapenem: permeability, binding to penicillin-binding proteins, and stability to hydrolysis by β-lactamases

5. Design, Synthesis, and Evaluation of a Potent Mechanism-Based Inhibitor for the TEM .beta.-Lactamase with Implications for the Enzyme Mechanism

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