Synthesis and potent anticonvulsant activities of 4-oxo-imidazo[1,2-a]indeno[1,2-e]pyrazin-8- and -9-carboxylic (acetic) acid AMPA antagonists-Reference-Cited by-同舟云学术

Synthesis and potent anticonvulsant activities of 4-oxo-imidazo[1,2-a]indeno[1,2-e]pyrazin-8- and -9-carboxylic (acetic) acid AMPA antagonists

Published:2000-12 Issue:24 Volume:10 Page:2749-2754
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Pratt Jeremy,Jimonet Patrick,Bohme Georg Andrees,Boireau Alain,Damour Dominique,Debono Marc Williams,Genevois-Borella Arielle,Randle John C.R,Ribeill Yves,Stutzmann Jean-Marie,Vuilhorgne Marc,Mignani Serge

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference18 articles.

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2. Global Ischemia Induces Downregulation of Glur2 mRNA and Increases AMPA Receptor-Mediated Ca2+Influx in Hippocampal CA1 Neurons of Gerbil

3. For a recent review, see: Chimirri, A.; Gitto, R.; Zappalà, M. Exp. Opin. Ther. Patents 1999, 9, 557, and references cited therein.

4. 6-(1H-Imidazol-1-yl)-7-nitro-2,3(1H,4H)-quinoxalinedione hydrochloride (YM90K) and related compounds: structure-activity relationships for the AMPA-type non-NMDA receptor

5. ZK200775: A phosphonate quinoxalinedione AMPA antagonist for neuroprotection in stroke and trauma

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