Design, synthesis, activity, and structure of a novel class of matrix metalloproteinase inhibitors containing a heterocyclic P2′-P3′ amide bond isostere-Reference-Cited by-同舟云学术

Design, synthesis, activity, and structure of a novel class of matrix metalloproteinase inhibitors containing a heterocyclic P2′-P3′ amide bond isostere

Published:1996-07 Issue:13 Volume:6 Page:1601-1606
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Chen Jian Jeffrey,Zhang Yiping,Hammond Scott,Dewdney Nolan,Ho Teresa,Lin Xiaohong,Browner Michelle F.,Castelhano Arlindo L.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference17 articles.

1. Matrix Metalloproteinases: A Review

2. Inhibition of Matrix Metalloproteinases by Hydroxamates Containing Heteroatom-Based Modifications of the P1' Group

3. On the size of the active site in proteases. I. Papain

4. Inhibition of matrix metalloproteinases by N-carboxyalkyl peptides

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