Peptidyl epoxides as inhibitors of α-chymotrypsin: Remarkable change from irreversible to reversible competitive inhibitor as a consequence of the improvement of binding affinity-Reference-Cited by-同舟云学术

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Peptidyl epoxides as inhibitors of α-chymotrypsin: Remarkable change from irreversible to reversible competitive inhibitor as a consequence of the improvement of binding affinity

Published:1996-12 Issue:23 Volume:6 Page:2837-2840
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Kim Dong H.,Li Zhi-Hong,Lee Soo Suk

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference20 articles.

1. The Enzymes;Blow,1971

2. The Enzymes;Hess,1971

3. Enzymes;Dixon,1979

4. Chapter 20. Proteinases in Inflammation

Cited by 4 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Peptidyl epoxides extended in the P′ direction as cysteine protease inhibitors: Effect on affinity and mechanism of inhibition;Bioorganic & Medicinal Chemistry;2008-10

2. Inactivation of cysteine proteases by peptidyl epoxides: characterization of the alkylation sites on the enzyme and the inactivator;BIOCHEM J;2000

3. Design of protease inhibitors on the basis of substrate stereospecificity;Biopolymers;1999

4. Inhibition of papain with 2-benzyl-3,4-epoxybutanoic acid esters. Mechanistic and stereochemical probe for cysteine protease catalysis;Bioorganic & Medicinal Chemistry;1997-11

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