The design and biological evaluation of a series of 3-hydroxy-3-methylglutaryl coenzyme a (HMG-CoA) reductase inhibitors related to dihydromevinolin.-Reference-Cited by-同舟云学术

The design and biological evaluation of a series of 3-hydroxy-3-methylglutaryl coenzyme a (HMG-CoA) reductase inhibitors related to dihydromevinolin.

Published:1992-01 Issue:3 Volume:2 Page:223-228
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Bone Elisabeth A.,Cunningham Emer M.,Davidson Alan H.,Galloway W.Alan,Lewis Christopher N.,Morrice Elizabeth M.,Reeve Maxwell M.,Todd Richard S.,White Ingrid M.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference20 articles.

1. HMG-CoA Reductase Inhibitors for Treatment of Hypercholesterolemia

2. Crystal and molecular structure of compactin, a new antifungal metabolite from Penicillium brevicompactum

3. ML-236A, ML-236B, and ML-236C, new inhibitors of cholesterogensis produced by Penicillium citrinum.

4. Mevinolin: a highly potent competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase and a cholesterol-lowering agent.

5. 3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors. 3. 7-(3,5-Disubstituted-[1,1'-biphenyl]-2-yl)-3,5-dihydroxy-6-heptenoic acids and their lactone derivatives

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1. The biosynthesis of steroids and triterpenoids;Natural Product Reports;1998

2. 3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibitors: oxime ether analogs of pravastatin;Bioorganic & Medicinal Chemistry;1995-11

3. The Chemistry and Total Synthesis of Mevinolin and Related Compounds;Recent Progress in the Chemical Synthesis of Antibiotics and Related Microbial Products Vol. 2;1993

4. Total synthesis of dihydromevinolin and a series of related 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors;The Journal of Organic Chemistry;1992-10