Synthesis, computer modeling and biological evaluation of novel protein kinase C agonists based on a 7-membered lactam moiety-Reference-Cited by-同舟云学术

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Synthesis, computer modeling and biological evaluation of novel protein kinase C agonists based on a 7-membered lactam moiety

Published:1999-01 Issue:2 Volume:9 Page:173-178
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Endo Yasuyuki,Shimazu Masako,Fukasawa Hiroshi,Driedger Paul E.,Kimura Kaname,Tomioka Nobuo,Itai Akiko,Shudo Koichi

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference27 articles.

1. The role of protein kinase C in cell surface signal transduction and tumour promotion

2. Activation of beta-isozyme of protein kinase C (PKC beta) is necessary and sufficient for phorbol ester-induced differentiation of HL-60 promyelocytes. Studies with PKC beta-defective PET mutant.

3. Protein Kinase C. Current Concepts and Future Perspectives,1992

4. Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

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2. Zinc‐Catalyzed Asymmetric Formal [4+3] Annulation of Isoxazoles with Enynol Ethers by 6π Electrocyclization: Stereoselective Access to 2 H ‐Azepines;Angewandte Chemie;2019-12-12

3. ChemInform Abstract: Synthesis, Computer Modeling and Biological Evaluation of Novel Protein Kinase C Agonists Based on a 7-Membered Lactam Moiety.;ChemInform;2010-06-15

4. Hybrid aza-steroid alkylators in the treatment of colon cancer;Cancer Letters;2006-11-18

5. The Effect of an Estrone D-Lactam Steroid Ester Derivative on Breast Cancer Cells and Its Predicted Binding Interactions With the Ligand Binding Domain of Estrogen Receptor-α;Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics;2006-03-01

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