C-Alkylated spiro[benzofuran-3(2H),4′-1′-methyl-piperidine-7-ols] as potent opioids: A conformation-activity study-Reference-Cited by-同舟云学术

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C-Alkylated spiro[benzofuran-3(2H),4′-1′-methyl-piperidine-7-ols] as potent opioids: A conformation-activity study

Published:1998-07 Issue:14 Volume:8 Page:1813-1818
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Tsai Ya-Ching,Liou Jing-Ping,Liao Richard,Cheng Chen-Yu,Tao Pao-Luh

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference11 articles.

1. Analgesics: Neurochemical, Behavioral, and Clinical Perspectives;Michne,1984

2. Chapter 2. Centrally Acting Analgesics

3. Novel radical synthesis of morphine fragments spiro[benzofuran-3(2H),4′-piperidine] and octahydro-1H-benzofuro[3,2-e]isoquinoline

4. Synthesis of morphine fragments spiro[benzofuran-3(2H),4′-piperidine] and octahydro-1H-benzofuro[3,2-e]isoquinoline by intramolecular Heck reaction

5. Structure-activity studies of morphine fragments. III. Synthesis, opiate receptor binding, analgetic activity and conformational studies of spiro-[tetralin-1,4′-piperidines]

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1. Regioselective synthesis of spirooxindole-pyrolidine via (GAP) chemistry process: Experimental and DFT study;Journal of Molecular Structure;2022-12

2. A concise, facile and MCR-GAP chemistry strategy for the synthesis of spiro[benzo[4,5]thiazolo[3,2-a]pyrano[2,3-d]pyrimidine-4,3′-indoline] derivatives as fluorescent cellular imaging agents;Journal of Molecular Structure;2021-12

3. Highly Facile, Regio‐ and Stereoselective Synthesis of Spiropyrrolidine‐5‐aza‐2‐oxindole Derivatives through Multicomponent 1,3‐Dipolar Cycloaddition Reaction and Their In‐Vitro and In‐Silico Biological Studies;ChemistrySelect;2021-09-15

4. Recent investigations in the synthesis of spirooxindole derivatives by Iranian researchers;Journal of the Iranian Chemical Society;2020-05-15

5. Synthesis and biological evaluation of new spirooxindoles with embedded pharmacophores;New Journal of Chemistry;2016

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