Nucleoside Analogues as Highly Potent and Selective Inhibitors of Herpes Simplex Virus Thymidine Kinase

Author:

Martin Joseph A,Lambert Robert W,Merrett John H,Parkes Kevin E.B,Thomas Gareth J,Baker Stewart J,Bushnell David J,Cansfield Julie E,Dunsdon Stephen J,Freeman Andrew C,Hopkins Richard A,Johns Ian R,Keech Elizabeth,Simmonite Heather,Walmsley Andrea,Wong Kai-In Philippe,Holland Mark

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference25 articles.

1. Spruance, S. L. In Clinical Management of Herpes Viruses; Sachs, S. L., Strauss, S. E., Whitley, R. J., Griffiths, P. D., Eds.; IOS: Washington, DC, 1995; pp 3–42.

2. Corey, L.; Wald, A. In Clinical Management of Herpes Viruses; Sachs, S. L., Strauss, S. E., Whitley, R. J., Griffiths, P. D., Eds.; IOS: Washington, DC, 1995; pp 43–53.

3. Role of Herpes simplex Virus Thymidine Kinase Expression in Viral Pathogenesis and Latency

4. Induction of Both Thymidine and Deoxycytidine Kinase Activity by Herpes Viruses

5. Thymidine kinase-negative herpes simplex virus mutants establish latency in mouse trigeminal ganglia but do not reactivate.

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