Synthesis of an α-Aminophosphonate Nucleoside as an Inhibitor of S-Adenosyl-l-Homocysteine Hydrolase

Author:

Steere Jennifer A,Sampson Peter B,Honek John F

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference37 articles.

1. S‐Adenosylmetliionine and methylation

2. Design and synthesis of S-adenosylhomocysteine hydrolase inhibitors as broad-spectrum antiviral agents

3. (a) Takusagawa, F.; Fujioka, M.; Spies, A.; Schowen, R. L. In Comprehensive Biological Catalysis: A Mechanistic Reference; Sinnott, M., Ed.; Academic: San Diego, 1998; p 1.

4. Enzymatic dna methylation in higher eukaryotes

5. S-Adenosyl-L-homocysteine hydrolase as a target for antiviral chemotherapy

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