Conformational restriction of methionyl tRNA synthetase inhibitors leading to analogues with potent inhibition and excellent gram-Positive antibacterial activity-Reference-Cited by-同舟云学术

Conformational restriction of methionyl tRNA synthetase inhibitors leading to analogues with potent inhibition and excellent gram-Positive antibacterial activity

Published:2003-04 Issue:7 Volume:13 Page:1265-1268
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Jarvest Richard L.,Berge John M.,Brown Pamela,Houge-Frydrych Catherine S.V.,O'Hanlon Peter J.,McNair David J.,Pope Andrew J.,Rittenhouse Stephen

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference11 articles.

1. Clinical Prevalence, Antimicrobial Susceptibility, and Geographic Resistance Patterns of Enterococci: Results from the SENTRY Antimicrobial Surveillance Program, 1997–1999

2. Nanomolar Inhibitors of Staphylococcus aureus Methionyl tRNA Synthetase with Potent Antibacterial Activity against Gram-Positive Pathogens

3. Jarvest, R. L.; Berge, J. M.; Brown M. J.; Brown, P.; Elder, J. S.; Forrest, A. K.; Houge-Frydrych, C. S. V.; O'Hanlon, P. J.; McNair, D. J.; Rittenhouse, S.; Sheppard, R. J. Bioorg. Med. Chem. Lett. 2003, 13, 665.

4. Catalyst® 3.1 Accelrys Inc. www.accelrys.com.

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