Phase 1 trials of molecular targeted therapies: Are we evaluating toxicities properly?
Author:
Publisher
Elsevier BV
Subject
Cancer Research,Oncology
Reference5 articles.
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3. Randomized phase II study of multiple dose levels of CCI-779, a novel mammalian target of rapamycin kinase inhibitor, in patients with advanced refractory renal cell carcinoma;Atkins;J Clin Oncol,2004
4. Workshop on phase I study design Ninth NCI/EORTC New Drug Development Symposium, Amsterdam, March 12, 1996;Arbuck;Ann Oncol,1996
5. Le Tourneau C, et al. Heterogeneity in the definition of dose-limiting toxicity in phase I cancer clinical trials of molecularly targeted agents: a review of the literature. Eur J Cancer, this issue.
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