Randomised phase 2 study comparing the efficacy and safety of the oral tyrosine kinase inhibitor nintedanib with single agent ifosfamide in patients with advanced, inoperable, metastatic soft tissue sarcoma after failure of first-line chemotherapy: EORTC-1506-STBSG “ANITA”

Author:

Schöffski PatrickORCID,Toulmonde Maud,Estival AnnaORCID,Marquina GloriaORCID,Dudzisz-Śledź Monika,Brahmi Mehdi,Steeghs Neeltje,Karavasilis VasiliosORCID,de Haan JaccoORCID,Wozniak AgnieszkaORCID,Cousin Sophie,Domènech Marta,Bovée Judith V.M.G.,Charon-Barra Céline,Marreaud Sandrine,Litière Saskia,De Meulemeester LauraORCID,Olungu Christine,Gelderblom Hans

Funder

Boehringer Ingelheim International GmbH

European Organisation for Research and Treatment of Cancer

Publisher

Elsevier BV

Subject

Cancer Research,Oncology

Reference43 articles.

1. National Comprehensive Cancer Network. NCCN guidelines 1.2021 soft tissue sarcoma. Available at: https://www.nccn.org/professionals/physician_gls/pdf/sarcoma_blocks.pdf’.

2. Descriptive epidemiology of sarcomas in Europe: report from the RARECARE project;Stiller;Eur J Canc,2013

3. Treatment of advanced, metastatic soft tissue sarcoma: latest evidence and clinical considerations;In;Ther Adv Med Oncol,2017

4. Soft tissue and visceral sarcomas: ESMO-EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up;Casali;Ann Oncol,2018

5. Soft tissue and bone tumours,2020

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