Phase I feasibility study for intrathecal administration of trastuzumab in patients with HER2 positive breast carcinomatous meningitis

Author:

Bonneau Claire,Paintaud Gilles,Trédan Olivier,Dubot CoralineORCID,Desvignes CélineORCID,Dieras Véronique,Taillibert Sophie,Tresca PatriciaORCID,Turbiez IsabelleORCID,Li Jacques,Passot Christophe,Mefti Fawzia,Mouret-Fourme Emmanuelle,Le Rhun EmilieORCID,Gutierrez Maya

Funder

Roche group

Publisher

Elsevier BV

Subject

Cancer Research,Oncology

Reference28 articles.

1. Breast cancer leptomeningeal metastasis–the role of multimodality treatment;Rudnicka;J Neurooncol,2007

2. Brain metastases: the HER2 paradigm;Lin;Clin Canc Res Off J Am Assoc Canc Res,2007

3. Cardiotoxicity and incidence of brain metastases after adjuvant trastuzumab for early breast cancer: the dark side of the moon? A meta-analysis of the randomized trials;Bria;Breast Cancer Res Treat,2008

4. Ratio of trastuzumab levels in serum and cerebrospinal fluid is altered in HER2-positive breast cancer patients with brain metastases and impairment of blood-brain barrier;Stemmler;Anticancer Drugs,2007

5. Efficacy of intracerebral microinfusion of trastuzumab in an athymic rat model of intracerebral metastatic breast cancer;Grossi;Clin Cancer Res Off J Am Assoc Cancer Res,2003

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