Phase 0 (zero) clinical trials: More than zero benefit?

Author:

Schellens Jan H.M.

Publisher

Elsevier BV

Subject

Cancer Research,Oncology

Reference9 articles.

1. The price of innovation: new estimates of drug development costs;DiMasi;J Health Econ,2003

2. Slow start to phase 0 as researchers debate value;Twombly;J Natl Cancer Inst,2006

3. Can the pharmaceutical industry reduce attrition rates?;Kola;Nat Rev Drug Discov,2004

4. Goodall S. Rising to the productivity challenge: a strategic framework for Biopharma. The Boston Consulting Group Report 2004. .

5. Risk in new drug development: approval success rate for investigational drugs;DiMasi;Clin Pharmacol Ther,2001

Cited by 4 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Designing Safer and Greener Antibiotics;Antibiotics;2013-09-04

2. Essais cliniques exploratoires de phase 0 : état de la littérature 2006-2009;Bulletin du Cancer;2011-07

3. MICRODOSING: A NEW STRATEGY FOR DRUG DEVELOPMENT PROCESS;International journal of pharmaceutical sciences and research;2011-07-01

4. Healthy volunteers and early phases of clinical experimentation;European Journal of Clinical Pharmacology;2010-05-12

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