Prevalence and implications of significance testing for baseline covariate imbalance in randomised cancer clinical trials: The Table 1 Fallacy

Author:

Sherry Alexander D.,Msaouel PavlosORCID,McCaw Zachary R.ORCID,Abi Jaoude Joseph,Hsu Eric J.,Kouzy Ramez,Patel RoshalORCID,Yang Yumeng,Lin Timothy A.,Taniguchi Cullen M.,Rödel ClausORCID,Fokas Emmanouil,Tang Chad,Fuller Clifton David,Minsky Bruce,Meirson TomerORCID,Sun Ryan,Ludmir Ethan B.

Funder

Andrew Sabin Family Foundation

National Institutes of Health

Fund for Innovation in Cancer Informatics

National Cancer Institute

University of Texas MD Anderson Cancer Center

Publisher

Elsevier BV

Subject

Cancer Research,Oncology

Reference40 articles.

1. Comparability of randomised groups;Altman;J R Stat Soc Ser D (The Statistician),1985

2. Epidemiologic methods in clinical trials;Rothman;Cancer,1977

3. Understanding and misunderstanding randomized controlled trials;Deaton;Soc Sci Med,2018

4. Cluster size variability and imbalance in cluster randomized controlled trials;Carter;Stat Med,2010

5. Seven myths of randomisation in clinical trials;Senn;Stat Med,2013

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