Osimertinib versus osimertinib plus chemotherapy for non–small cell lung cancer with EGFR (T790M)-associated resistance to initial EGFR inhibitor treatment: An open-label, randomised phase 2 clinical trial
Author:
Funder
AstraZeneca
Publisher
Elsevier BV
Subject
Cancer Research,Oncology
Reference19 articles.
1. AZD9291, an irreversible EGFR TKI, overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer;Cross;Canc Discov,2014
2. AZD9291 in EGFR inhibitor-resistant non-small-cell lung cancer;Janne;N Engl J Med,2015
3. Osimertinib or platinum-pemetrexed in EGFR t790m-positive lung cancer;Mok;N Engl J Med,2017
4. Mechanisms of osimertinib resistance and emerging treatment options;Schmid;Lung Canc,2020
5. Emerging treatment paradigms for EGFR-mutant lung cancers progressing on osimertinib: a review;Piper-Vallillo;J Clin Oncol,2020
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