C677T and A1298C MTHFR polymorphisms, a challenge for antifolate and fluoropyrimidine-based therapy personalisation

Author:

De Mattia Elena,Toffoli Giuseppe

Publisher

Elsevier BV

Subject

Cancer Research,Oncology

Reference106 articles.

1. Methylenetetrahydrofolate reductase;Rosenblatt;Clin Invest Med,2001

2. A common mutation in the methylenetetrahydrofolate reductase gene is associated with an accumulation of formylated tetrahydrofolates in red blood cells;Bagley;Proc Natl Acad Sci USA,1998

3. Common methylenetetrahydrofolate reductase gene mutation leads to hyperhomocysteinemia but not to vascular disease: the result of a meta-analysis;Brattstrom;Circulation,1998

4. A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase;Frosst;Nat Genet,1995

5. Association of total plasma homocysteine with methylenetetrahydrofolate reductase genotypes 677C>T, 1298A>C, and 1793G>A and the corresponding haplotypes in Swedish children and adolescents;Bottiger;Int J Mol Med,2007

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