Sequence-dependent cross-resistance of combined radiotherapy plus BRAFV600E inhibition in melanoma

Author:

Shannan B.,Matschke J.,Chauvistré H.,Vogel F.,Klein D.,Meier F.,Westphal D.,Bruns J.,Rauschenberg R.,Utikal J.,Forschner A.,Berking C.,Terheyden P.,Dabrowski E.,Gutzmer R.,Rafei-Shamsabadi D.,Meiss F.,Heinzerling L.,Zimmer L.,Livingstone Elisabeth,Váraljai Renáta,Hoewner A.,Horn S.,Klode J.,Stuschke M.,Scheffler B.,Marchetto A.,Sannino G.,Grünewald T.G.P.,Schadendorf D.ORCID,Jendrossek V.,Roesch A.

Funder

Deutsche ForschungsgemeinschaftDeutsche Forschungsgemeinschaft (DFG, German Research Foundation)

Hiege Foundation

Monika-Kutzner Foundation

German Cancer Aid

Publisher

Elsevier BV

Subject

Cancer Research,Oncology

Reference46 articles.

1. Melanoma;Schadendorf;Nat Rev Dis Primers,2015

2. Tumor heterogeneity and plasticity as elusive drivers for resistance to MAPK pathway inhibition in melanoma;Roesch;Oncogene,2015

3. Efficacy of anti-PD-1 therapy in patients with melanoma brain metastases;Parakh;Br J Canc,2017

4. Outcomes in melanoma patients treated with BRAF/MEK-Directed therapy or immune checkpoint inhibition stratified by clinical trial versus standard of care;Goldman;Oncology,2017

5. Combination controversies: checkpoint inhibition alone or in combination for the treatment of melanoma?;Warner;Oncology (Williston Park),2018

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