Effect of Sirolimus on Immune Reconstitution Following Myeloablative Allogeneic Stem Cell Transplantation: An Ancillary Analysis of a Randomized Controlled Trial Comparing Tacrolimus/Sirolimus and Tacrolimus/Methotrexate (Blood and Marrow Transplant Clinical Trials Network/BMT CTN 0402)

Author:

Gooptu Mahasweta,Kim Haesook T.,Howard Alan,Choi Sung W.,Soiffer Robert J.,Antin Joseph H.,Ritz Jerome,Cutler Corey S.

Publisher

Elsevier BV

Subject

Transplantation,Hematology

Reference21 articles.

1. Pathophysiology of chronic graft-versus-host disease and therapeutic targets;Zeiser;N Engl J Med,2017

2. Phase 3 study comparing methotrexate and tacrolimus with methotrexate and cyclosporine for prophylaxis of acute graft-versus-host disease after marrow transplantation from unrelated donors;Nash;Blood,2000

3. Sirolimus: its discovery, biological properties, and mechanism of action;Sehgal;Transplant Proc,2003

4. Tacrolimus (FK506) and sirolimus (rapamycin) in combination are not antagonistic but produce extended graft survival in cardiac transplantation in the rat;Vu;Transplantation,1997

5. Sirolimus, tacrolimus, and low-dose methotrexate for graft-versus-host disease prophylaxis in mismatched related donor or unrelated donor transplantation;Antin;Blood,2003

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