IL-2–Targeted Therapy Ameliorates the Severity of Graft-versus-Host Disease: Ex Vivo Selective Depletion of Host-Reactive T Cells and In Vivo Therapy

Author:

Yarkoni Shai,Prigozhina Tatyana B.,Slavin Shimon,Askenasy Nadir

Funder

Frankel Trust for Experimental Bone Marrow Transplantation and Target-In Ltd

Publisher

Elsevier BV

Subject

Transplantation,Hematology

Reference79 articles.

1. Graft-versus-host disease;Shlomchik;Nat Rev Immunol,2007

2. Graft-versus-host disease;Ferrara;Lancet,2009

3. Immunoregulation of GVHD by triggering the innate immune system with CpG;Morecki;Expert Rev Hematol,2009

4. Transplantation of HLA-haploidentical T cell-depleted marrow for leukemia addition of cytosine arabinoside to the pretransplant conditioning prevents rejection;Bozdech;Exp Hematol,1985

5. Bone marrow transplantation with T-cell–depleted grafts, I: reconstitution of immunohemopoietic functions in lethally irradiated mice transplanted with unseparated or T-cell–depleted syngeneic bone marrow grafts;Shalit;Transplantation,1986

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