The small molecule activator S3969 stimulates the epithelial sodium channel by interacting with a specific binding pocket in the channel's β-subunit
Author:
Funder
Deutsche Forschungsgemeinschaft
Publisher
Elsevier BV
Reference76 articles.
1. International Union of Basic and Clinical Pharmacology. XCI. structure, function, and pharmacology of acid-sensing ion channels and the epithelial Na+ channel;Kellenberger;Pharmacol. Rev.,2015
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3. Incorporation of the delta-subunit into the epithelial sodium channel (ENaC) generates protease-resistant ENaCs in Xenopus laevis;Wichmann;J. Biol. Chem.,2018
4. Evolution of epithelial sodium channels: current concepts and hypotheses;Wichmann;Am. J. Physiol. Regul. Integr. Comp. Physiol.,2020
5. Membrane topology of the epithelial sodium channel in intact cells;Canessa;Am. J. Physiol.,1994
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