A novel inhibitor rescues cerebellar defects in a zebrafish model of Down syndrome–associated kinase Dyrk1A overexpression-Reference-Cited by-同舟云学术

A novel inhibitor rescues cerebellar defects in a zebrafish model of Down syndrome–associated kinase Dyrk1A overexpression

Published:2021-07 Issue:1 Volume:297 Page:100853
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Buchberger Astrid,Schepergerdes Lena,Flaßhoff Maren,Kunick Conrad^ORCID,Köster Reinhard W.^ORCID

Funder

German Research Foundation

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference71 articles.

1. Minibrain: A new protein kinase family involved in postembryonic neurogenesis in Drosophila;Tejedor;Neuron,1995

2. A human homologue of Drosophila minibrain (Mnb) is expressed in the neuronal regions affected in Down syndrome and maps to the critical region;Guimerâ;Hum. Mol. Genet.,1996

3. Functional screening of 2 Mb of human chromosome 21q22.2 in transgenic mice implicates minibrain in learning defects associated with Down syndrome;Smith;Nat. Genet.,1997

4. The Down syndrome-related protein kinase DYRK1A phosphorylates p27Kip1 and Cyclin D1 and induces cell cycle exit and neuronal differentiation;Soppa;Cell Cycle,2014

5. Minibrain drives the dacapo-dependent cell cycle exit of neurons in the Drosophila brain by promoting asense and prospero expression;Shaikh;Development,2016

Cited by 4 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Lifelong regeneration of cerebellar Purkinje cells after induced cell ablation in zebrafish;eLife;2023-04-12

2. Proteomic profiling reveals mitochondrial dysfunction in the cerebellum of transgenic mice overexpressing DYRK1A, a Down syndrome candidate gene;Frontiers in Molecular Neuroscience;2022-12-15

3. Lifelong regeneration of cerebellar Purkinje neurons after induced cell ablation in zebrafish;2022-05-10

4. Differential maturation and chaperone dependence of the paralogous protein kinases DYRK1A and DYRK1B;Scientific Reports;2022-02-14