The mTORC2/AKT/VCP axis is associated with quality control of the stalled translation of poly(GR) dipeptide repeats in C9-ALS/FTD-Reference-Cited by-同舟云学术

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The mTORC2/AKT/VCP axis is associated with quality control of the stalled translation of poly(GR) dipeptide repeats in C9-ALS/FTD

Published:2023-03 Issue:3 Volume:299 Page:102995
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Li Yu,Geng Ji,Rimal Suman,Wang Haochuan,Liu Xiangguo,Lu Bingwei,Li Shuangxi

Funder

National Institutes of Health

Shandong University

National Natural Science Foundation of China

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference67 articles.

1. Converging mechanisms in ALS and FTD: disrupted RNA and protein homeostasis;Ling;Neuron,2013

2. ALS and FTD: where RNA metabolism meets protein quality control;Mandrioli;Semin. Cell Dev. Biol.,2020

3. How do C9ORF72 repeat expansions cause amyotrophic lateral sclerosis and frontotemporal dementia: can we learn from other noncoding repeat expansion disorders?;van Blitterswijk;Curr. Opin. Neurol.,2012

4. Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS;DeJesus-Hernandez;Neuron,2011

5. A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD;Renton;Neuron,2011

Cited by 4 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Ribosomal quality control factors inhibit repeat-associated non-AUG translation from GC-rich repeats;Nucleic Acids Research;2024-02-27

2. Metformin ameliorates mitochondrial damage induced by C9orf72 poly(GR) via upregulating AKT phosphorylation;Journal of Cellular Biochemistry;2024-01-17

3. Translation dysregulation in neurodegenerative diseases: a focus on ALS;Molecular Neurodegeneration;2023-08-25

4. Ribosomal quality control factors inhibit repeat-associated non-AUG translation from GC-rich repeats;2023-06-07

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