Human cytochrome P450 17A1 structures with metabolites of prostate cancer drug abiraterone reveal substrate-binding plasticity and a second binding site-Reference-Cited by-同舟云学术

Human cytochrome P450 17A1 structures with metabolites of prostate cancer drug abiraterone reveal substrate-binding plasticity and a second binding site

Published:2023-03 Issue:3 Volume:299 Page:102999
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Petrunak Elyse M.,Bart Aaron G.,Peng Hwei-Ming,Auchus Richard J.,Scott Emily E.

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference27 articles.

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3. Novel steroidal inhibitors of human cytochrome P45017α (17α-hydroxylase-C17,20-lyase): potential agents for the treatment of prostatic cancer;Potter;J. Med. Chem.,1995

4. Structures of cytochrome P450 17A1 with prostate cancer drugs abiraterone and TOK-001;DeVore;Nature,2012

5. Structures of human steroidogenic cytochrome P450 17A1 with substrates;Petrunak;J. Biol. Chem.,2014

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